3+ day, 13+ hour ago   (128+ words) Table 1: Summary of contamination types in NGS data, with characteristic data signatures and recommended analytical detection tools. Reads with unexpected or mismatched index combinations Unique dual index audit, per-library read-count review A systematic approach for evaluating a sample flagged for…...

3+ day, 13+ hour ago   (156+ words) Mapped 5' start position Mapped start position and UMI sequence Distinguishes independent molecules at the same position Appropriate for WGS germline variant calling Yes, with added overhead Appropriate for deep targeted panel sequencing No; removes genuine fragments Yes, via consensus calling…...

4+ day, 15+ hour ago   (200+ words) Technology Networks Connect these carbon triangles to an amine, a functional group with a nitrogen at its center, and you get aminocyclopropanes. They are of particular interest in pharmaceutical research because they can be used to replace another substructure commonly…...

1+ week, 3+ day ago   (457+ words) Evolution has created an astonishing amount of diversity, shaping much of our understanding of biology. But this diversity, which took billions of years to emerge, barely scratches the surface of what could have existed given the trillions of possible DNA…...