31+ min ago   (171+ words) clinicaltrialvanguard.com CMO Location Drives Site Selection for Parkinsonian Imaging Trial When a radiopharmaceutical expires within hours of manufacture, the drug’s chemistry, not the disease’s prevalence, decides where a trial can run. That constraint shaped every decision in a site…...

1+ hour, 4+ min ago   (464+ words) Every living cell depends on thousands of distinct protein families, each folding into precise three-dimensional shapes to carry out the molecular tasks that sustain life....

1+ hour, 12+ min ago   (90+ words) Artificial intelligence has become an increasingly powerful tool in the search for new medicines, but a persistent problem has haunted the field: neural networks that invent molecules are remarkably creative yet notoriously unreliable. They can propose chemical structures that look…...

6+ hour, 58+ min ago   (307+ words) We’ve all been there: digging through a cluttered medicine cabinet, wondering if that half-empty blister pack of Ibuprofen is still safe to take, or if it will play nice with the cold medicine you just bought. In the age of…...

3+ hour, 43+ min ago   (95+ words) Every seed is a masterpiece of biological engineering, a compact package in which molecular order and cellular design are woven together to protect and nourish a future plant. For scientists trying to understand how crops such as the yellow pea…...

4+ hour, 32+ min ago   (92+ words) This June, ten of the life sciences industry’s most respected board members came to New York for Accenture’s second annual Life Sciences Board Forum for something this industr... Ten life sciences board directors on AI's three hardest questions: developing the…...

5+ hour, 37+ min ago   (679+ words) For most of modern biology, the hunt for new human proteins has followed a familiar path: read the genetic sequence, predict where genes begin and end, and work outward from there. That strategy has served science remarkably well, delivering the…...

6+ hour, 20+ min ago   (746+ words) A sweeping new review published in Discover Chemistry charts the remarkable rise of proteolysis-targeting chimeras, better known as PROTACs, from a bold theoretical idea to one of the most closely watched platforms in modern drug discovery. Written by Sandip G....

2+ day, 17+ hour ago   (884+ words) One implication of this progress is that pharma companies are using AI to unlock potential treatments for smaller and smaller patient populations, as in for rarer diseases and conditions that traditionally would not be a priority. Indeed, over the past…...

11+ hour, 19+ min ago   (432+ words) Unicorns, dragons, pixies, and the like are the stuff of kids' stories, or at least they should be. But now a new Texas startup, a bioengineering firm, The Embryo Corporation, is looking at the possibility of producing these creatures for…...